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The main urinary metabolites, apparently pharmacologically inactive, are produced by hydrolytic dehalogenation and deamination followed by glucuronidation (Levy, 1974

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Indeed, decreased GSDME expression in oral squamous cell carcinoma (OSCC) is associated with poor prognosis (176).Thus, this evidence suggests that GSDME mediated pyroptosis plays an essential role in tumor suppression

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Microbiota signaling pathways that influence neurologic disease

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2020;217:e20192195

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