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Description

Bone morphogenetic proteins prevent bone marrow stromal cell-mediated oligodendroglial differentiation of transplanted adult neural progenitor cells in the injured spinal cord

Cagrilintide is being explored as part of this approach, especially in combination with GLP-1 based therapies

Moreover, the antidepressant paroxetine has been reported to modulate P4HB expression in neural cells [36], suggesting a role for P4HB in the mechanism of antidepressant action