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Ethanol directly induced HMGB1 release through NOX2/NLRP1 inflammasome in neuronal cells

Although sGC activator therapy has been shown to be efficacious in our model and in a broad variety of other preclinical disease models, human trials with the sGC activator were halted early because of systemic hypotension (43)

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Maher et al., 2021a)

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