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After that, plasma concentrations of NAC declined rapidly in both groups

9, 26 It is also worth noting that BSO has been used in several clinical trials associated with anticancer drugs, and it is well tolerated by patients

However, due to the extensive cross-talk of KRAS-mediated signalling pathways, it is difficult to achieve effective inhibition of signalling pathways only by inhibiting a single key molecule, and joint inhibition of multiple key molecules is often required

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