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Death receptor 5 and Bcl-2 protein expression as predictors of tumor response to gemcitabine and cisplatin in patients with advanced non-small-cell lung cancer

In the case of ischemic stroke, reactive astrocytes also contribute to BBB permeability through the Wnt/-catenin pathway as demonstrated in an Nhe1 conditional knockout mouse model 119

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In apoptosis, CHOP initiates the caspase cascade by altering the balance of Bcl-2 family proteins (promoting BIM/PUMA expression and suppressing Bcl-2) [6,7,8,9]