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Furthermore, the large size and negative charge of siRNA hamper its penetration across the cell membrane and prevent its intracellular accumulation 19,20

The cells in the bone mainly include osteoblasts, osteoclasts, and bone marrow mesenchymal stem cells (27)

O., Kassem, D

doi: 10.1042/0264-6021:3440253 222 Cortese-KrottMMKulakovLOplnderCKolb-BachofenVKrnckeK-DSuschekCV

Results Metabolic activity and cytotoxicity We compared rotenone-induced toxicity in the two salmonid gill epithelial cell lines, RTgill-W1 (Rainbow trout) and ASG-10 (Atlantic salmon)