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Consistent with previous reports 36 , exposure to e-cigarette aerosol or tobacco smoke extracts alone, at the doses used in this study, did not increase cell growth (Figure S1ac)

The crystals form due to supersaturation of uric acid in the tissues, which results from hyperuricemia 1

Once you become addicted to nicotine, it rewires your brain and causes a significant decrease in the natural dopamine your body produces and releases

The Framingham risk score for coronary heart disease 3,4 , which includes smoking, advanced age, hypertension, diabetes, and dyslipidemia as significant prognostic factors, highlights the substantial impact of smoking on CVD development

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