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To experimentally assess the functional consequences of our nrf2a5 mutated allele, we tested its ability to activate the transcription of an ARE-driven firefly luciferase reporter gene following a previously published protocol (Mukaigasa et al, 2012)

patients who received IV thrombolysis at morning (06001200) and afternoon (12001800 h) time points exhibited less improvement on the NIH Stroke Scale compared to other time points

Pfalzer AC, Choi SW, Tammen SA, Park LK, Bottiglieri T, Parnell LD, Lamon-Fava S

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The through-line in all of these is a familiar mechanism of hype: a real but limited laboratory observation is amplified, stripped of its qualifiers, sometimes attributed to the wrong molecule (AHK-Cu results claimed for GHK-Cu), and then presented with a precise-sounding statistic that implies clinical certainty