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By restoring gut barrier function, KPV prevents the translocation of bacterial endotoxins from the intestinal lumen into the bloodstream

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As examples, some of these predictions are stated here: Under conditions of B12 insufficiency, excess folic acid intake will cause the following: Diversion of holoTC from serum to hemopoietic cells to support reticulocyte proliferation Loss of holoTC in urine due to interference of its reuptake by the megalin-receptor complex in the renal tubules Reduced availability of holoTC to the liver, brain, and other tissues due to its diversion to the hemopoietic system and loss in the urine

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Wat ze vonden: 4 192 humane genen veranderen hun expressie met 2 in reactie op GHK-Cu (31,2 % van het humane genoom) Daarvan 2 296 genen up-gereguleerd , 1 896 down-gereguleerd Patroon: verjongende signatuur, genen typisch geassocieerd met veroudering worden down-gereguleerd, regeneratieve genen up-gereguleerd DNA-reparatie , sterke up-regulatie van genen van BER, HR, NER routes Mitochondriale biogenese , verhoging van het aantal mitochondrin in de cellen Anti-apoptotisch signaal , bescherming tegen celdood Down-regulatie van kankersignalen , sommige oncogenen werden verlaagd Waarom dit belangrijk is: Dit is het sterkste bewijs voor de pleiotrope aard van GHK-Cu