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Folate receptor expression was reduced by 43% due to exposure to fumonisin B1

Treatment with glucagon-like peptide-1 receptor agonists and incidence of dementia: data from pooled double-blind randomized controlled trials and nationwide disease and prescription registers

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For this purpose, 2 g of Sephadex G-50 fine was swollen in 50 mL HEPES buffer (10 mM, pH 7.4) overnight at room temperature and packed into 3 mL disposable syringes with a Whatman filter at the bottom

Comparison of GT2 domains with and without donor substrates highlighted a conformational rearrangement of the otherwise flexible C-terminus of the domain for residues 562580, wrapping around the donor substrate binding cavity and positioning the backbone carbonyl of residue Ser569 and Thr571 in a productive conformation for hydrogen bonding with both phosphates of the UDP donor substrate (Fig