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doi: 10.1016/j.bbadis.2016.11.005 118 QinSDengFWuWJiangLYamashiroTYanoSet al

MDACCs ORBIT Biologics Facility

Exhibits a plasma halflife of roughly 2 hours, creating sharp, controllable GH pulses suitable for timelocked studies around sleep, feeding, or exercise

Peptide origin / Partial sequence of human gastric protein BPC, isolated from gastric juice Molecular weight / Approximately 1,419 Da (15 amino acids) Common off-label oral dose / 250 to 500 mcg twice daily, taken on an empty stomach Common off-label subcutaneous dose / 200 to 300 mcg once or twice daily near the affected area or abdominally Evidence level / Preclinical only (GRADE: very low certainty for human GI healing) Key preclinical finding / Accelerated gastric ulcer healing in rats within 24 to 72 hours across multiple models Route preference for GI targets / Oral administration, based on topical mucosal contact rationale Safety profile in humans / Largely unknown

Composed of 15 amino acids, this bpc-157 peptide was first characterized in the 1990s for its apparent protective effects on the digestive system