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Biomedical Research and Clinical Diagnostics: In biomedical research, FAME analysis contributes to the characterization of lipid metabolism in health and disease

Inhibition of hypoxia-induced autophagy was shown to disrupt pSTAT3 signaling through accumulation of p62, which selectively induces pSTAT3 degradation by the proteasome system and thereby restores cytotoxic T-cell mediated killing of tumor cells (273)

The phosphorylated SOD1 then translocates to the nucleus, where, by binding to gene promoters, it controls the transcription of genes related to oxidative stress resistance (156)