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A comparative LC-MS study was performed to evaluate the pharmacokinetics of senkyunolide I in rats following administration of a modified Huoluo Xiaoling Dan formulation vs

All datasets generated and/or analyzed during this study are provided in Supplementary Data 1

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Diffusion dynamics across the FB-OOC To determine the flow of materials and their kinetics, as well as to measure cell barrier function, dextran beads (molecular weight = 3,000 kDa) were utilized to determine hydrostatic pressure across the device

As previously described 21 , four microliters (4 g) of reconstituted peptides were loaded and washed on a Pepmap100 C18 trap (5 m, 0.3 5.0 mm, Thermo Fisher Scientific, Waltham, MA, USA) at a flow rate of 20 L/min