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-, overall negative effects

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It is required for mitochondrial energy metabolism, normal nervous system function, red blood cell development and maturation, DNA synthesis and the methylation cycle, and has antioxidant effects at the cellular level

Introduction Streptococcus pneumoniae is a Gram-positive bacterium that typically colonizes the human nasopharynx

Blood-brain barrier (BBB) is a semipermeable membrane barrier situated between the bloodstream and brain, with the role to regulate the influx and efflux of exogenous compounds and xenobiotics into the brain, or biological substances needed for brain metabolic activity and neuronal function [38]