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The final step involves the removal of 5caC from the DNA, which is carried out by DNA repair mechanisms (44)

Adam also reflects on leadership, decision-making under uncertainty, and what it takes to build trust across cycles

35 Myopathic cramps are almost always exertional, presenting with exercise intolerance, myoglobinuria, and exertional cramps

We propose that intrinsic defects in cellular metabolism cause epithelial dysfunction (metabolic injury) evoking attempts of the ISC niche to reconstitute normal tissue architecture and function

Kondratov RV, Kondratova AA, Gorbacheva VY, Vykhovanets OV, Antoch MP (2006) Early aging and age-related pathologies in mice deficient in BMAL1, the core component of the circadian clock