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Furthermore, macrophage activation by LPS is dependent on glycolysis, as inhibition of glycolysis with 2-deoxyglucose (2DG) decreases the inflammatory response, whereas inhibitors of mitochondrial respiration have no such effect, consistent with the fact that oxidative metabolism is already shut down under such conditions 38

10.1097/JSA.0000000000000115 261 WesslerS.Meisner-KoberN

h , Quantification of the nuclei is based on their circularity ratio, as depicted in (Fig

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