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[PubMed: 1621866] 187

The suns energy is more diffused in the winter sunlight, and the result is often felt in our energy levels and well-being

It directly stimulates anorexigenic POMC neurons and inhibits adjacent orexigenic NPY neurons in the ARC of the hypothalamus, thus promoting satiety, increasing energy expenditure, and resulting in weight loss (6)

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Laboratories studying cartilage matrix biology, chondrocyte proliferation and differentiation, and growth factor signalling in musculoskeletal research models have incorporated this fragment as an experimental variable representing an expanding research frontier beyond its primary metabolic applications