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Vitaglione P., Morisco F., Mazzone G., Amoruso D

FIGURE 1 4.2 Hyperbaric oxygen affects the contents of exosomes Prior research has demonstrated that hypoxic treatment of mesenchymal stem cells alters the mix of microRNAs and proteins in exosomes generated by these cells, hence augmenting the therapeutic potential of the exosomes ( Moreover, another research has demonstrated that hyperbaric oxygen can influence the expression of inflammation-associated genes in exosomes (refer to Table 1)

[DOI] [PubMed] [Google Scholar] 34.Uchida Y., Takio K., Titani K., Ihara Y., Tomonaga M

On the contrary, a subsequent randomized phase 2 trial investigated the receipt of eltrombopag during standard induction therapy in AML patients and found no clinical benefit of eltrombopag but rather a tendency for increased severe adverse events (164)

The molecule is encapsulated inside protective fatty lipids, preventing it from being devoured by digestive enzymes