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Macrophage studies demonstrate that GHK-Cu administration shifts these cells from a pro-inflammatory M1 phenotype to a tissue-repairing M2 phenotype, increasing their production of growth factors including vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) by 40-60%

10.1016/j.sleep.2023.09.026 11 HasegawaE.MiyasakaA.SakuraiK.CherasseY.LiY.SakuraiT

Sequences of primers for qRT-PCR are listed in Supplementary Table 2

GHK-Cus established wound healing benefits support faster recovery from such interventions while promoting optimal scarring outcomes