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Although techniques such as micro-dialysis and cerebral open flow micro-perfusion allow for real-time, continuous, and accurate measurement of drug concentration and distribution of nanocarriers in the brain, they are highly dangerous to the human body

Recovery in chronic brain ischemia: In a study in 30 chronic brain ischemia patients, a combination of Semax, ADP, and collagen yielded better recovery outcomes, emphasizing Semax's neurotrophic and anti-platelet effects [25]

Related Ang IV analogues were studied as well, such as Nle-Ang IV 2 (Nle-Tyr-Ile-His-Pro-Phe) and the endogenous LVV-hemorphin-7 3 (Leu-Val-Val-Tyr-Pro-Trp-Thr-Gln-Arg-Phe), both with structural similarities to Ang IV at the N-terminal part of the peptides (Figure 1)

Very responsive and helpful

The strategies to address senescent cells and replenish exhausted stem cells during the aging process, as well as supplementing metabolic substances like NAD+, gene therapy, or epigenetic approaches to mitigate aging, are different because they aim to promote the repair of senescent cells rather than inducing their apoptosis (Covarrubias et al., 2020