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Long-term efficacy and safety of pegcetacoplan over 36 months including 12-month results of the GALE open-label extension study

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IV Glutathione Therapy In more severe cases, intravenous (IV) glutathione therapy has been used to deliver glutathione directly into the bloodstream, bypassing digestive barriers

Cerebral glucose uptake is reduced in patients, with distinct metabolic patterns observed across genetic backgrounds (SOD1, C9ORF72, and sporadic ALS), suggesting region-specific vulnerabilities 13