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Some in vitro studies looked into the efficacy of other chemotherapeutic drugs to inhibit growth of FISS cell lines, such as the proteasome inhibitor bortezomib (Laver et al., 2022), but in vivo studies are missing

Further complications such as necrosis, amputation, or renal failure may arise

When we proposed to establish the APP for the CY 2021 performance period, we proposed to require that MIPS eligible clinicians who reported the APP would be scored on all measures in the APP quality measure set (85 FR 50285)