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There was a registered trial, NCT02637284, and the title was: PCO-02-Safety and Pharmocokinetics Trial

164 However, excessive mitophagy can lead to a significant loss of mitochondrial content, potentially triggering cell death

This cortisol arousal response is remarkably absent in patients suffering from a severe form of ME/CFS (273), from Post-Traumatic Stress Disease (PTSD) (283)