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M.LupuA.et al (2023)

Examples of these other birth control methods include: medroxyprogesterone (Depo-Provera) injection copper intrauterine device (IUD) (Paragard) etonogestrel and ethinyl estradiol (NuvaRing) vaginal ring norelgestromin and ethinyl estradiol (Xulane) patch If switching birth control methods isnt an option (or you prefer not to), your doctor may recommend that you use a barrier method of contraception, such as a condom, along with your birth control pills

J Am Soc Nephrol 2005;16:3553-62

ACE2, a crucial enzyme of the renin-angiotensin-aldosterone system (RAAS), is expressed in multiple organs all over the system and is vital in sustaining blood pressure and cardiovascular, renal, immune, and nervous system homeostasis

This prolonged activation makes it powerful, but also requires a more thoughtful approach to timing and dosing