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Positive contribution of hydroxytyrosol-enriched wheat bread to HbA(1)c levels, lipid profile, markers of inflammation and body weight in subjects with overweight/obesity and type 2 diabetes mellitus

In conclusion, this study elucidates the significant role of DP in alleviating sciatica pain by protein microarray and experimental validation, The potential mechanism involves downregulating the expression of key inflammatory mediators IL-6 and CINC-3, thereby inhibiting neutrophil migration and promoting neuroprotection through the upregulation of CNTF(Fig

Moreover, hypoxia-induced signaling pathways facilitate adaptive modifications in erythrocyte metabolism, encompassing changes in glycolytic flux and levels of 2,3-bisphosphoglycerate (2,3-BPG), which influence oxygen delivery efficacy