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TGF- as a key modulator of astrocyte reactivity: disease relevance and therapeutic implications

Verkerke H, Horwath M, Saeedi B, Boyer D, Allen JW, Owens J, Arthur CM, Nakahara H, Rha J, Patel K, Wu SC, Paul A, Yasin N, Wang J, Shin S, Brown D, Normile K, Cole L, Meyers M, Lin H, Woods E, Isaac J, Broder K, Wade J, Kauffman RC, Patel R, Josephson CD, Reynolds S, Sherman M, Wrammert J, Alter D, Guarner J, Roback JD, Neish A, Stowell SR (2021) Comparison of antibody class specific SARS-CoV-2 serology for the diagnosis of acute COVID-19

Glutathione has been utilized in the treatment of various conditions such as Parkinson's disease, Alzheimer's disease, cancer, and HIV/AIDS

It crosses the cell membrane and translocates to the nucleus under metabolic stress, where it regulates nuclear gene expression tied to glucose metabolism and oxidative capacity

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