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naturalnews.com/046401_magn

Many factors can contribute to reduced or cessation of normal thiamine production in ruminants

Given that both IGF-I and IGFBP-3 are rapidly cleared from the circulation if unbound, using the IGF-I/IGFBP-3 ratio and disregarding IGF-II concentrations (that are 2-3-fold those of IGF-I on a molar basis) does not make any sense