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PCAF-mediated acetylation of LDHB at K82 was found to significantly decrease its enzymatic activity and impair hepatic lactate clearance, resulting in lactate accumulation, which exacerbates lipid deposition and inflammatory responses by activating histone hyperacetylation in high-fat diet (HFD)-induced NAFLD

Moderate oxidative stress promotes epithelial-mesenchymal transition in the lens epithelial cells via the TGF-/Smad and Wnt/-catenin pathways

Fragment screening at AstraZeneca: developing the next generation biophysics fragment set

Prehospital administration of hydroxocobalamin for smoke inhalation - associated cyanide poisoning: 8 years of experience in the Paris Fire Brigade

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