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The sudden influx of oxygen and nutrients leads to the generation of reactive oxygen species, activation of inflammatory pathways, and subsequent cellular damage

Many industrial toxins selectively target and elicit oxidative damage in mitochondria [49], which are vulnerable owing to a relative deficiency in DNA repair mechanisms [171]

They directly influence cancer cell mitochondria by secreting antibodies and cytokines that can alter the mitochondrial membrane potential

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doi: 10.1017/S0033291708005096