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moderate evidence] Cardiovascular Diabetology 2018: Cardiovascular disease risk factor responses to a type 2 diabetes care model including nutritional ketosis induced by sustained carbohydrate restriction at 1 year: an open label, non-randomized, controlled study [weak evidence] American Journal of Clinical Nutrition 2007: A low-glycemic-load diet improves symptoms in acne vulgaris patients: a randomized controlled trial [moderate evidence] This review article discusses the theory and the science behind this potential effect: Skin Pharmacology and Physiology 2012: Nutrition and acne: therapeutic potential of ketogenic diets [overview article

Researchers may refer to the following peer-reviewed sources: Raun K, Hansen BS, Johansen NL, et al

Rosenfeldt et al., 2013)

A more oxidized state is observed in obese compared with lean subjects or in response to high fat feeding (Table 2, increases occur in the ketones, acetoacetate plus -hydroxybutyrate, from less than 0.1 mM to more than 7 mM