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Among the proteins with increased expression in ME/CFS were 3-hydroxybutyrate dehydrogenase type 1 (BDH1) and acetyl-CoA acetyltransferase 2 (ACAT2), both of which are integral to fatty acid metabolism and processing of ketone bodies

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In the CY 2026 OPPS/ASC proposed rule (90 FR 33775), we proposed to align with the case threshold exemption from the Medicare Promoting Interoperability Program (77 FR 54080), the Hospital IQR Program (79 FR 50324), and the Hospital OQR Program (86 FR 63869)