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Step 3 Identify the cause The treatment approach differs significantly between dietary and absorption-related deficiency

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J., Nersissian A., Gralla E

Ipamorelin Synonyms / Designations: Ipamorelin, Ipamorelin Acetate, NNC 26-0161, Ipamorelin pentapeptide CAS Number: 170851-70-4 Molecular Formula: C38H49N9O5 Molecular Weight: ~711.85 g/mol Peptide Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH2 Peptide Classification: Synthetic growth hormone secretagogue

(Eur J Endocrinol 1998) reported that ipamorelin stimulated GH release from anterior pituitary somatotrophs via GHSR-1a (Gq/11PLCIP pathway) at doses up to 200-fold its GH-effective dose without significantly elevating ACTH, cortisol, FSH, LH, prolactin, or TSH above GHRH-stimulated controls in rats