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Given melatonins well-established antioxidant properties and its ability to modulate mitochondrial function [22, 25], we hypothesize that melatonin may influence cuproptosis and ferroptosis in ovarian cells, potentially mitigating the effects of aging on oocyte quality and improving reproductive outcomes

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Multiple SNPs near and in the TMEM106B gene, including the SNPs associated with neurodegenerative diseases described above, such as rs1990622, rs6966915, and rs1020004, are in strong linkage disequilibrium (LD), constituting two common TMEM106B haplotypes, one associated with increased disease risk, and the other with a protective effect [10, 78] (Fig

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Freckles It is the first type of skin spotting people notice, often during childhood or teenage years