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Even more intriguing is the presentation of right forelimb sparing and disability (reacting with only left or no forelimb upon challenge with forceps have difficulty with maintaining body balance while rearing), common in cuprizone rats, not presented in BPC 157-cuprizone rats (normal functioning of right forelimb, simultaneous reaction with both forelimbs, and grasp the forceps, and maintain body balance while rearing as healthy rats)

This observation could indicate a potential role of GHK-Cu in limiting the activation or mobilization of neutrophils, possibly curtailing the oxidative bursts and consequent inflammation

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The peptide reduces inflammatory cytokine activity without suppressing the immune response entirely, according to a review published in the International Journal of Molecular Sciences