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Pregnancy-associated plasma protein-a is the insulin-like growth factor binding protein-4 protease secreted by human ovarian granulosa cells and is a marker of dominant follicle selection and the corpus luteum

Reprogramming in vivo produces teratomas and iPS cells with totipotency features

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Animal-to-human amount translation is not straightforward and requires allometric scaling, and human pharmacokinetics, safety, and efficacy remain uncharacterized in published literature

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