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10 Conclusions and future directions Female reproductive disorders remain a major global health challenge, with limited innovative therapeutic options, underscoring the urgent need for multi-target agents capable of addressing the intertwined endocrine, metabolic, inflammatory, and fibrotic pathways that drive disease progression

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The methods used for the supplemental figures are described in the Supplemental Methods

It is completed by the child's primary caregiver

Association between exposure to perchlorate and blood serum thyrotropin (TSHthe pituitary hormone being the main stimulatory factor for thyroid hormone synthesis