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10.1007/s43152-021-00030-3 130 PaisR.CharlotteF.FedchukL.BedossaP.LebrayP.PoynardT.et al (2013)

We then investigated the biological functions of MAT2A in OS through both in vitro and in vivo experiments

While our in vitro results show a putative role for senescence in immune cell functional changes during killifish aging, whether the molecular and cellular changes occurring in the killifish kidney marrow during aging lead to systemic functional consequences remains to be assessed in more detail

But there are a few points to be mentioned here: It depends on the target protein's structure, location, and other characteristics