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Primary outcomes included changes in pain intensity (regarding low back pain and radicular leg pain) measured using the visual analogue scale (VAS), and functional improvement assessed by walking distance until symptoms appeared [63]

Vitamin B12, also known as cobalamin, is an essential nutrient that plays a key role in red blood cell production, nerve function, and DNA synthesis

TB500 has been evaluated in animal models, typically at doses of 250500 mcg per injection or 6 mg/kg body weight , administered multiple times weekly