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Efficacy and Safety The therapeutic potential and safety profile of Ipamorelin are evaluated in animal models of various diseases or conditions

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Accordingly, the contact with MM cell lines, as well as MM-derived conditioned media, triggered a marked decrease in lipid accumulation in differentiating murine pre-adipocytes, which displayed gene expression changes in steroid biosynthesis, cell cycle and metabolism (oxidative phosphorylation and glycolysis) and a marked increase of typical MM-supportive genes, including IL-6 and CXCL12

Furthermore, amplifications of clinically actionable target genes such as ERBB2 and myeloid leukaemia cell differentiation protein (MCL1) are also common in brain-tropic metastatic cells