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LPS-induced cytokine production in human monocytes and macrophages

Can ketones compensate for deteriorating brain glucose uptake during aging

Pooling data from some of the trials showed an increase in serum coenzyme Q 10 concentrations (three studies) but no effect on left ventricular ejection fraction (two studies) or exercise capacity (two studies) (33)

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However, if the amounts of acetyl-CoA generated in fatty acid -oxidation challenge the processing capacity of the TCA cycle or if activity in the TCA cycle is low due to low amounts of intermediates such as oxaloacetate, acetyl-CoA is then used instead in biosynthesis of ketone bodies via acetoacyl-CoA and -hydroxy--methylglutaryl-CoA (HMG-CoA)