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AGXT overexpression curbs hepatic steatosis by inducing FAO To explore potential mechanisms by which oxalate lowering via AGXT overexpression ameliorates MASH, we performed unbiased RNA sequencing of livers from mice treated with AAV8-GFP or AAV8-AGXT following 24 weeks on the MASH diet

PMID: 16807549.10.1038/sj.ki.5000394 [PubMed: 16807549] [CrossRef] 58

As conventional anti-inflammatories have poor blood brain-barrier permeability, we expect centrally active immune modulators to be an area of interest in the future