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Transplacental passage of azithromycin was initially postulated to occur at low rates [145], but further pharmacokinetic studies have proven adequate penetration into the amniotic fluid with adequate doses, dosing intervals and duration of therapy [146]

Cardiovascular Effects Some studies have documented temporary changes in heart rate or blood pressure, particularly in subjects with pre-existing cardiovascular conditions

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Why Preclinical Results Cannot Resolve the Salt Question Animal studies may investigate BPC-157 under a particular formulation, but they do not establish that every commercial salt form has the same: Purity Stability Absorption Impurity profile Pharmacokinetics Safety A salt-form claim must therefore be supported by evidence concerning that exact material rather than by BPC-157 literature in general

10.1038/s41586-019-1707-0 21 DolmaS.LessnickS