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Description

Understanding the functioning of the antioxidant system in eukaryotic cells is important for the assessment of factors that may affect the pro- and antioxidant balance

doi: 10.1007/s10863-020-09859-z

In breast cancer, increased circCDYL2 stabilizes GRB7, preventing its degradation and boosting its interaction with FAK, which sustains AKT and ERK1/2 pathway activity, leading to trastuzumab resistance