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10.1039/c5ra26797h 290 WinterbournC

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According to these results, EVs generated under stress may contain chemical cues that improve cellular reactions meant to safeguard and promote oocyte development in the face of environmental stressors [251]

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That may be a hard pass

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For example, the - Glutamyl tri-peptide, glutathione (-Glu-cys-gly) that is critical for redox and other functions is very abundant in eukaryotes

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SAM is the universal methyl donor for DNA methylation, histone methylation, and hundreds of other methylation reactions that regulate gene expression

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