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While the Akt/eNOS, NOX and Nrf2 pathways have been widely studied in the literature, it has been shown that phenolic compounds can modulate various cellular functions indirectly related to the redox balance regulation, such as inflammation or endothelial dysfunction (Reference Ruskovska, Maksimova and Milenkovic71)

F., Simonsen, C

In psoriasis, T cells together with their cytokines and chemokines are shown to induce serious inflammation by Th1- and Th17-driven immune response including IL-20, IL-23, IL-12, IL-17 and IL-22 [2, 3, 4, 5]

Therefore, further research on these compounds, including their isolation, structural elucidation, and characterization, is needed to evaluate their efficacy and safety

Addressing these factors requires a multifaceted approach that includes lifestyle changes, which can be difficult for some patients to adhere to