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Annu Rev Pharmacol Toxicol 47:89116

Am Soc Clin Oncol Educ Book 34: e497e502 Dang CV (2013) MYC, metabolism, cell growth, and tumorigenesis

New York: Springer133

For the approved semaglutide products, there is a ~100-fold increase in weekly dose requirements when switching from the typical dose of SC administration (1 mg) to oral (98 mg), 5 reflecting a considerable manufacturing cost challenge for the latter