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Approximately 15% of the nanoprobe crossed BBB and entered the brain parenchyma, which was much higher than the levels reachable by the traditional pathways 12,13

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New York: McGraw-Hill, 2006 Kliegman RM, Behrman RE, Jenson HB, et al

Functionally, NMDA receptors localized extrasynaptically on dendritic shafts bind extrasynaptic L-glu and mediate Ca 2+ influx upon relief of the Mg +2 block by dendrite depolarization upon backfiring of action potentials (Wu et al., 2012)