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SIRT3 deficiency exacerbates fatty liver by attenuating the HIF1alpha-LIPIN 1 pathway and increasing CD36 through Nrf2

Chorobom tym towarzyszy stres oksydacyjny, ktry silnie obcia funkcje mitochondriw i powoduje wysokie zuycie glutationu, prowadzc do jego niedoborw, co z kolei skutkuje brakiem ochrony tkanek mzgu 8