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In this context, carriers of apolipoprotein 4 (APOE4) allele, a major risk factor for AD, present with pericyte degeneration and associated BBB breakdown [42], which has been recently associated with cognitive decline, independent of AD pathology [43]

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Lo que se ha investigado Angiognesis reportada En literatura preclnica se asocia al eje VEGFR2/eNOS/NO y a la formacin de vasos nuevos

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Finally, with respect to N 2 O, the reservoirs primarily acted as sinks, likely due to efficient denitrification processes in the sediments that reduce N 2 O to N 2