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Graphical abstract First-line biologic therapy selection highly impacts ulcerative colitis outcomes: results from the APPETISER study Table 1

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Form & Analytical Testing CJC-1295 no DAC 5mg + Ipamorelin 5mg is supplied as a synthetic dual-peptide research material manufactured under controlled production standards to support consistency, purity, and structural stability during laboratory handling and evaluation

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Dietary modification with increased fibre intake, alternatives to antibiotics, use of pre- and pro-biotics, and vitamin D supplementation, to restore levels of beneficial microbes such as Lactobacillus and Bifidobacterium , might rebalance gut dysbiosis and help repair barrier damage in CRC patients